Subacute thyroiditis is an inflammatory disease of the thyroid gland. Women are affected much more often than men. It usually occurs between the ages of 30 and 50.
Causes
The disease may develop after viral infections such as coxsackie virus, influenza, or adenoviral infections.
General Symptoms
• Fatigue
• Weakness
• Headache
• Muscle pain
• Joint pain
Stages of the Disease
Subacute thyroiditis generally progresses through three stages.
Stage 1 – Hyperthyroidism
During this phase, the following symptoms are observed:
• Palpitations
• Weight loss
• Nervousness
• Tremor
• Enlargement of the thyroid gland
• Pain in the thyroid area radiating to the neck, occiput, ears, or lower jaw
• Sometimes difficulty swallowing
• Enlargement of lymph nodes
• Fever
Over time, hyperthyroidism is replaced by the
second (euthyroid) stage
, during which the clinical symptoms subside. A third (hypothyroid) stage
may also occur, which is usually temporary.
The course of the disease lasts from several weeks to a few months.
Diagnosis
Diagnosis includes:
•
Laboratory tests
– complete blood count, C-reactive protein level, and thyroid hormone tests.
•
Thyroid ultrasound (US)
– the gland appears heterogeneous and hypoechoic.
•
Thyroid scintigraphy
– damaged areas may appear as “cold nodules.”
•
Fine-needle aspiration biopsy
– performed for histological examination.
Treatment
Subacute thyroiditis usually resolves spontaneously within up to 12 months.
• For mild pain symptoms, nonsteroidal anti-inflammatory drugs (NSAIDs) are used.
• In more severe cases, glucocorticoids are prescribed and must be taken only according to a medical regimen.
• During the hyperthyroid phase, beta-adrenergic blockers are indicated.
• In the hypothyroid phase, replacement therapy with thyroid hormones is rarely necessary.
Conclusion