Prolactin

Prolactin

Prolactin
Prolactin is a hormone produced by your pituitary gland, which is located at the base of your brain. Prolactin helps a woman’s breasts grow and develop, as well as milk production (lactation) after childbirth. Both men and women normally have small amounts of prolactin in their blood. Prolactin levels are regulated by other hormones called prolactin-inhibiting factors, such as dopamine. During pregnancy, prolactin levels increase due to the effects of sex hormones (mainly estradiol).
Elevated levels of prolactin in the blood are called hyperprolactinemia. Hyperprolactinemia can cause fertility problems in both men and women. Oligomenorrhea, amenorrhea, and infertility in women with hyperprolactinemia, as well as impotence and oligospermia in men with hyperprolactinemia, are caused by the suppression of gonadotropin-releasing hormone secretion by prolactin.

Hyperprolactinemia

is one of the most common endocrine disorders and can be caused by lactotroph adenomas (prolactinomas, which account for approximately 40% of pituitary tumors), drug-induced or pathological disruption of the hypothalamic-pituitary dopaminergic pathway, and can sometimes be idiopathic.
Low levels of prolactin in the blood can be caused by abnormal development of lactotroph cells (genetic causes), destruction of pituitary tissue (Sheehan's syndrome, inflammatory or autoimmune damage to lactotrophs, tumor or surgery, tuberculosis), pseudohypoparathyroidism, idiopathic prolactin deficiency, medication (e.g., dopamine agonists).
Emotional stress, exercise, and a high-protein diet can stimulate prolactin secretion.

Thus, the physiological causes of hyperprolactinemia are

:

1

.Pregnancy,

2

.Breastfeeding,

3

.Stress.

The pathological causes of hyperprolactinemia are:

1.Lactotroph adenomas - prolactinomas

2.Other disorders of the hypothalamus and pituitary gland

3 Medications

4.Mutation of the prolactin receptor gene

5.

Other causes

: idiopathic hyperprolactinemia, hypothyroidism, chest wall injury, chronic kidney disease and macroprolactinemia.


When to check the level of prolactin in the blood

1

.During symptoms of prolactinoma (headaches, blurred vision, galactorrhea);

2

.To monitor the development of prolactinoma

3

.In case of infertility and sexual dysfunction in women and men;

4

.In case of low testosterone levels in men;

5

.In case of suspicion of general pituitary insufficiency (in combination with a growth hormone test)

6

.When the patient is taking medications that affect dopamine production (to monitor changes in prolactin levels).

Patient preparation

Do not take multivitamins or biological supplements containing biotin (vitamin B7), which is usually contained in supplements and multivitamins for hair, skin and nails, for 12 hours before sampling.

Sampling: 

Venous blood

Deadline for response: 

Same day

Knowing your prolactin level can help detect potential hormonal imbalances early and support your reproductive and overall health. Visit Dalimed MC for a quick and accurate prolactin test—your well-being is our priority.
Polisegmental osteochondrosis
02 August 2025
Polisegmental osteochondrosis is a disease of the musculoskeletal system in which several or even all parts of the spine are affected. Because the painful sensations manifest differently in various parts, the disease is often confused with other ailments, so a thorough diagnosis is essential. This disease progresses much more difficultly than the usual form of osteochondrosis, as it causes rather mixed symptoms. Common symptoms include headache, dizziness, unprovoked nausea, and back pain that often radiates to the limbs. The causes of polisegmental osteochondrosis include: • Spinal trauma, which is usually associated with professional activity, an accident, or constant sports activities. Any damage to the musculoskeletal system does not pass without consequences, and the development of this disease is one of them. • Excessive body weight, as extra pounds create an increased load on the vertebrae, which leads to their rapid wear and provokes degenerative changes. • Incorrect posture. In young people, the disease is provoked by poor nutrition, being constantly in a bent position, scoliosis, or prolonged sitting at a computer desk. • Heredity. If a similar disorder was observed in close relatives, there is a high probability of it being passed down. • Lack of physical activity. The body must receive sufficient load every day for nutrients to enter the bones through diffusion from soft tissues. But if there is none, the metabolism is disturbed, which leads to the onset of degenerative processes in the bones. • Age-related changes. This is one of the most common causes, as the natural aging process of the body gradually leads to various negative changes, including degenerative processes in the cartilage. • Poor nutrition. The deficiency of minerals and vitamins in the body should also not be underestimated, as without them, all vital organs cannot develop normally. The symptoms of the disease depend on its location. Polisegmental osteochondrosis of the cervical spine is characterized by the following signs: • Acute pains that last long enough and are poorly eliminated by pain medications. • Hearing loss and periodically appearing sharp pains. • Sudden increase or decrease in blood pressure. • Frequent dizziness. • Impaired vision, the appearance of floating spots before the eyes. • Difficulty swallowing or speech problems. • The appearance of nausea, not related to a violation of the gastrointestinal tract. Damage to the thoracic spine is less common, as this area is less mobile than others. The distinguishing features in this case are the absence of bright signs, especially at the beginning of the process. The only characteristic sign is intercostal neuralgia, which a doctor can detect during the initial examination. If left untreated, thoracic osteochondrosis will gradually make itself known with severe pain, cough with bronchospasms, and pressure in the heart area. These symptoms are often confused with pleurisy or pathologies of the heart muscle. The degenerative process in the lumbar spine develops quickly and makes itself known even in the early stages. This is explained by the maximum load on this area, which includes the entire body weight and the heavy objects a person lifts every day. Symptoms include: • Severe pain radiating to the lower limbs. • Increased discomfort when trying to sit down or bend over. • Lack of relief even in a relaxed position. • Frequent bowel disorders or failures in the work of the pelvic organs. • Increased weakness in the legs or loss of skin sensation. • Difficulty in urination or defecation. • Chronic aching pains or sharp pains in the lower back. Upon the appearance of the first signs of pathology, it is necessary to make an appointment with a neuropathologist. The following methods are used to diagnose the disease: ultrasound, echography, MRI, X-ray, and Doppler of blood vessels. Treatment usually includes several directions at once, such as taking medications, strictly following a diet, physical therapy or visiting a manual therapist, acupuncture, therapeutic gymnastics, and unconventional medicine. The latter includes acupressure, hirudotherapy, manual therapy, and pharmacopuncture. PRP therapy is also used, which is the newest way to stimulate restorative processes. If the disease is not treated, it can lead to muscle dystrophy, acute circulatory failure, nerve entrapment, protrusions, and intervertebral hernias. Therefore, it is extremely important to be attentive to your health and see a doctor on time when the first symptoms appear. Don’t postpone taking care of your spine health. At Dalimed Medical Center, you will receive professional diagnostics and effective treatment under the supervision of experienced specialists.
Stress: The Silent Killer
25 July 2025
Stress is a natural response to challenges but chronic stress can seriously harm your health. It increases the risk of mental disorders like anxiety and depression, cardiovascular diseases, sleep problems, digestive issues, memory difficulties, and more. When stressed, your brain releases adrenaline and cortisol. These hormones prepare your body for fight-or-flight by opening airways, increasing blood flow to muscles and brain, raising heart rate, tensing muscles, and activating the immune system. While useful short-term, prolonged exposure raises blood sugar and risks such as diabetes and hypertension.Types of Stress Acute stress is short-lived and can help performance or survival. Chronic stress persists over time from ongoing problems like financial worries, relationship issues, or health conditions. Chronic stress needs managing to avoid serious health effects. Health Effects of Chronic Stress Chronic stress is linked to: • High blood pressure • Heart attacks and strokes • Diabetes • Irritable bowel syndrome • Skin conditions like eczema • Anxiety and depression • Infertility Controlling stress can help prevent or reduce symptoms of these conditions. Signs of Excessive StressSymptoms include: • Headaches, muscle pain, jaw stiffness • Fatigue and low energy • Skin rashes or acne • Digestive problems (nausea, diarrhea, constipation) • Blurry vision • Weakened immunity and frequent illness • Changes in sexual drive and menstrual cycle • Weight gain or loss • Sleep problems and dizziness • Anxiety, nervousness, restlessness • Difficulty concentrating or remembering • Increased use of alcohol or drugs If stress interferes with daily life or causes panic attacks, consult a healthcare provider. How to Manage Stress Engage in regular physical activity, which releases mood-boosting endorphins, improves sleep, immune function, heart health, and energy. Exercise is especially beneficial for retired first responders to manage stress. Practice relaxation techniques such as deep breathing, meditation, yoga, tai chi, or massage. Maintain social connections and spend time with family and friends. Set time for hobbies and enjoyable activities. Write in a journal to express feelings. Ensure enough sleep and eat a balanced, nutritious diet rich in B vitamins, omega-3 fatty acids, and magnesium, which support brain function and mood regulation. Avoid tobacco, alcohol, and illicit drugs. Stretch muscles regularly to relieve tension and reduce stress hormone levels.Deep Breathing Deep breathing calms the nervous system by activating relaxation responses, lowering blood pressure, reducing anxiety, and improving lung function. Diaphragmatic breathing is a simple method: breathe deeply so your belly rises, then exhale slowly, making exhales twice as long as inhales, repeating for 10 minutes. Avoid Unhealthy Coping Passive activities like watching TV, internet browsing, or gaming may feel relaxing but can increase stress over time. Many turn to unhealthy habits such as excessive drinking or smoking to cope, which worsen health. Recognize and replace these with healthier behaviors. Professional help can aid breaking bad habits and managing stress. When to Seek Help If you are unsure whether stress is causing your symptoms, or if self-help is not enough, see a healthcare provider. Therapy can identify stress sources and teach coping strategies. Seek emergency help if you experience chest pain, shortness of breath, dizziness, or other heart attack signs.Though stress is inevitable, adopting healthy habits, seeking support, and making lifestyle changes can greatly reduce its impact. Regular exercise, relaxation practices, good nutrition, social support, and professional care form a comprehensive approach to stress management.
What is Cortisol?
23 July 2025
Cortisol is the main glucocorticoid synthesized in the fascicular zone of the adrenal cortex. Cortisol levels reflect acute, chronic, and diurnal changes in the body across various physiological and psychological states. Typically, the highest secretion of cortisol occurs in the second half of the night, reaching its maximum level in the early morning, after which cortisol levels decrease throughout the day, recording the lowest levels in the first half of the night. Cortisol plays an important role in regulating many crucial physiological processes, including energy metabolism, electrolyte balance, maintenance of blood pressure, immunomodulation, stress response, cell proliferation, as well as cognitive functions. The main part of cortisol circulates in the plasma bound to proteins: corticosteroid-binding globulin and albumin. The biologically active free fraction accounts for only 2-5% of total cortisol. High levels of cortisol can be detected during stress reactions, psychiatric disorders, obesity, diabetes mellitus, alcoholism, and pregnancy, which can cause diagnostic problems in patients with Cushing's syndrome. Low levels of cortisol are observed in patients with rare adrenal enzyme disorders and after prolonged stress. When blood cortisol levels are low, the hypothalamus in the brain releases corticotropin-releasing hormone (CRH), which in turn causes the pituitary gland to produce adrenocorticotropic hormone (ACTH). ACTH stimulates cortisol secretion, leading to an increase in blood cortisol levels. When cortisol levels rise, they begin to inhibit the release of CRH from the hypothalamus and ACTH from the pituitary gland. The causes of high cortisol (hypercortisolism) are: 1.Overproduction of ACTH due to a CRH-producing tumor, an ACTH-producing pituitary tumor (Cushing's disease), or other tumors. 2.Autonomous overproduction of glucocorticoids by the adrenal fascicular zone, for example, in the case of a tumor (Cushing's syndrome). Manifestations of hypercortisolism include: • increased arterial pressure. • weight gain with fat accumulation in the face, neck, and torso, while the limbs are relatively thin. • hyperglycemia. • suppression of the immune system (lymphopenia, eosinopenia). • decreased muscle mass. • osteoporosis. • thinning of the skin. • appearance of striae. • slow wound healing. The causes of low cortisol (hypocortisolism) are: • Addison's disease (primary adrenal insufficiency). • Secondary adrenal insufficiency. • Pituitary insufficiency. • Hypothalamic insufficiency. • Congenital adrenal hyperplasia (defects in enzymes involved in cortisol synthesis). If you’re experiencing any of the symptoms mentioned above or want to assess your hormonal balance, we recommend checking your cortisol levels at Dalimed Medical Center. Our modern laboratory and experienced professionals ensure accurate results and personalized care.
How to Choose the Right Toothbrush
22 July 2025
Brushing teeth is an important part of daily oral hygiene. And choosing the right toothbrush is the first step to making this ritual truly effective. Currently, there is a huge selection of toothbrushes on store shelves, and it's easy to get confused: which one is really right for you?Choosing a Toothbrush: What to Look For?Here are three key points to consider when choosing a toothbrush:1. Soft Bristles. The toothbrush should have soft bristles. Such brushes clean teeth and gums more gently, especially if you have sensitive enamel or a tendency to inflammation. Hard bristles might indeed be better at removing plaque, but with excessive pressure, they can damage enamel and even cause gum recession (their pulling away from the teeth). This, in turn, leads to exposed tooth roots and increased sensitivity to cold, hot, and certain foods.2. Small Brush Head. The shape of the brush head also plays an important role. It is better to choose brushes with a small head (for example, a rhomboid shape) — they penetrate more easily into hard-to-reach areas of the oral cavity, especially to the back teeth. The shape should be comfortable so that you can easily reach all tooth surfaces. This will make the brushing process not only effective but also pleasant.3. Electric Toothbrush. Although a regular manual toothbrush also copes with its task, an electric toothbrush can remove plaque significantly better. It is especially useful for cleaning hard-to-reach areas and simplifies the brushing process itself. In addition, many such models have a built-in two-minute timer — it helps to observe the brushing time recommended by dentists.Individual Approach to Toothbrush Selection.Depending on your individual characteristics and needs, you can choose a toothbrush that is best suited for you:•Sensitive teeth – pay attention to toothbrushes specifically designed for sensitive oral cavities. They usually have ultra-soft bristles and a gentle cleaning mode.•Orthodontic appliances – if you have braces or other appliances, choose toothbrushes with angled bristles or special models for orthodontic system care. They effectively clean the area around brackets and wires.•Additional functions – some toothbrushes are equipped with built-in tongue scrapers or gum massagers. These elements help to freshen breath and maintain gum health. It is also worth considering the shape of the handle, the comfort of the grip, and the design of the bristles. The main thing is that it should be comfortable and pleasant for you to use the brush every day.To be confident in your dental health and to choose the right oral care products, we recommend undergoing a preventive dental check-up. At the Dalimed Medical Center, you can receive qualified consultation and professional oral care. Take care of yourself in time — health begins with a smile.

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